TrialSignal
Clinical trial intelligence report
Open-label Phase I, Multi-center Study to Determine the Recommended Dose of CYAD-211 After a Non-myeloablative Preconditioning Chemotherapy in Multiple Myeloma Patients With Relapsed or Refractory Disease
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT04613557-Jul 28, 2026
NCT ID
NCT04613557
Status
ACTIVE_NOT_RECRUITING
Phase
Phase 1
Sponsor
Celyad Oncology SA
Executive brief
Investment-Ready Snapshot
CYAD-211 is an allogeneic anti-BCMA CAR-T cell therapy being developed by Celyad Oncology SA for the treatment of relapsed or refractory multiple myeloma (MM). The asset targets a significant unmet need in the MM market, particularly among patients who have exhausted multiple treatment options. The competitive landscape includes autologous CAR-T therapies and other BCMA-targeted agents, which may pose challenges in terms of market penetration. The trial's focus on safety and dose determination is critical for establishing a favorable risk-benefit profile, which will be essential for future commercialization strategies. Given the increasing interest in CAR-T therapies, successful outcomes could position Celyad favorably against established players in the field.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04613557
Indication
Relapse/Refractory Multiple Myeloma
Modality
protein therapy
Target
BCMA (B-cell maturation antigen)
Intervention
CYAD-211, Endoxan, Fludara
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.