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A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT02094729-Jul 28, 2026
NCT ID
NCT02094729
Status
COMPLETED
Phase
Phase 1
Sponsor
Eisai Co., Ltd.
Executive brief
Investment-Ready Snapshot
Eisai Co., Ltd.'s BAN2401 is positioned in the competitive landscape of Alzheimer's disease therapeutics, particularly targeting patients with mild cognitive impairment and mild Alzheimer's disease. The market for Alzheimer's treatments is substantial, driven by an aging population and increasing prevalence of the disease. However, the competitive environment includes several other amyloid-targeting therapies and disease-modifying agents. Successful outcomes from this trial could enhance Eisai's portfolio and provide a strategic advantage, particularly if BAN2401 demonstrates superior safety and efficacy compared to existing therapies. Diligence should focus on regulatory pathways, potential market access challenges, and ongoing developments from competitors in the Alzheimer's space.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02094729
Indication
Alzheimer's Disease
Modality
small molecule
Target
BAN2401 targets amyloid beta aggregates, specifically aiming to reduce amyloid plaque burden in the brain, which is associated with Alzheimer's disease pathology.
Intervention
BAN2401 2.5 mg/kg, BAN2401 5 mg/kg, BAN2401 10 mg/kg, Placebo
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.