TrialSignal
Clinical trial intelligence report
Down Regulation of Oxidant Induced Airway Inflammation Through Modulation of NRF2
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT01625130-Jul 28, 2026
NCT ID
NCT01625130
Status
COMPLETED
Phase
Completed
Sponsor
University of North Carolina, Chapel Hill
Executive brief
Investment-Ready Snapshot
The study investigates the efficacy of a sulforaphane-enriched supplement in modulating NRF2 to mitigate ozone-induced airway inflammation. Given the increasing prevalence of respiratory conditions and the growing interest in nutraceuticals, this research could position sulforaphane as a viable adjunct therapy in respiratory health. The findings may attract attention from pharmaceutical companies focusing on respiratory diseases and environmental health, as well as from dietary supplement manufacturers. Competitive landscape includes existing anti-inflammatory agents and emerging nutraceuticals targeting oxidative stress. Diligence should focus on regulatory pathways for dietary supplements versus pharmaceuticals, as well as potential partnerships with environmental health organizations.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01625130
Indication
Healthy
Modality
RNA therapy
Target
NRF2 (Nuclear factor erythroid 2-related factor 2)
Intervention
Broccoli sprout homogenate, alfalfa sprout homogenate
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.