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A Multicenter, Multiple-dose Escalation, Randomized, Double-blind, Placebo-controlled Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT07243171-Jul 28, 2026
NCT ID
NCT07243171
Status
RECRUITING
Phase
Phase 1/2
Sponsor
Hangzhou Sciwind Biosciences Co., Ltd.
Executive brief
Investment-Ready Snapshot
Ecnoglutide, an oral formulation targeting GLP-1 receptors, is positioned to address the growing obesity epidemic in China, where the prevalence of overweight and obesity is rising. The study's multicenter, randomized design enhances its credibility and potential for regulatory approval. Given the competitive landscape, including established GLP-1 receptor agonists like semaglutide and liraglutide, ecnoglutide's oral delivery may provide a significant differentiation point. The trial's focus on safety and pharmacokinetics will be critical for market acceptance and could influence pricing strategies. The estimated enrollment of 84 participants indicates a moderate scale for initial safety assessments, which may expedite subsequent phases if results are favorable.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07243171
Indication
Overweight and/or Obesity
Modality
small molecule
Target
Glucagon-like peptide-1 (GLP-1) receptor
Intervention
ecnoglutide tablets, placebo with matching dosage
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.