TrialSignal
Clinical trial intelligence report
An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jul 28, 2026
Report code
NCT02238925-Jul 28, 2026
NCT ID
NCT02238925
Status
COMPLETED
Phase
Phase 2
Sponsor
Jazz Pharmaceuticals
Executive brief
Investment-Ready Snapshot
Jazz Pharmaceuticals' CPX-351 is positioned in a competitive landscape focused on acute leukemias and MDS, which are areas of significant unmet medical need. The drug's unique liposomal formulation may provide a therapeutic advantage over traditional chemotherapy, potentially leading to improved patient outcomes. The successful completion of this Phase II trial could enhance Jazz's portfolio and market presence, especially if the results demonstrate a favorable safety and efficacy profile. Given the stringent eligibility criteria and the focus on QTc prolongation, the asset may attract interest from regulatory bodies and investors, particularly in light of the growing emphasis on cardiac safety in oncology treatments.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02238925
Indication
Acute Myeloid Leukemia (AML)
Modality
small molecule
Target
CPX-351 (Cytarabine:Daunorubicin) is designed to target acute leukemias and myelodysplastic syndromes (MDS) through a liposomal formulation that enhances the pharmacokinetics and pharmacodynamics of its components.
Intervention
CPX-351
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.