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Clinical trial intelligence report
A Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of Chaperone-mediated Protein Degrader RNK05047 in Subjects With Advanced Solid Tumors (CHAMP-1)
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 25, 2026
Report code
NCT05487170-Jun 25, 2026
NCT ID
NCT05487170
Status
RECRUITING
Phase
Phase 1/2
Sponsor
Ranok Therapeutics (Hangzhou) Co., Ltd.
Executive brief
Investment-Ready Snapshot
Ranok Therapeutics is advancing RNK05047, a novel chaperone-mediated protein degrader, through a Phase 1/2 clinical trial targeting advanced solid tumors, including DLBCL. The asset is positioned in a competitive landscape that includes other emerging therapies focused on protein degradation, a promising area in oncology. The trial's focus on patients refractory to standard therapies highlights a significant unmet need, potentially enhancing market access and reimbursement prospects. Successful outcomes could lead to strategic partnerships or acquisition interest, particularly given the increasing investment in targeted therapies and novel modalities in oncology.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT05487170
Indication
Advanced Solid Tumor
Modality
protein therapy
Target
Chaperone-mediated protein degradation mechanism, specifically targeting proteins involved in advanced solid tumors, including DLBCL.
Intervention
RNK05047
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.