TrialSignal
Clinical trial intelligence report
A Phase 1, Crossover Study to Evaluate the Pharmacokinetics of Corplex™ Donepezil 10 mg Transdermal Delivery System Applied to Different Body Locations
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 25, 2026
Report code
NCT03432195-Jun 25, 2026
NCT ID
NCT03432195
Status
COMPLETED
Phase
Phase 1
Sponsor
Corium, Inc.
Executive brief
Investment-Ready Snapshot
Corium, Inc. is advancing its Corplex™ Donepezil transdermal delivery system (TDS) aimed at improving pharmacokinetic profiles for Alzheimer's Disease treatment. The transdermal route may enhance patient compliance compared to oral formulations, addressing a significant market need in Alzheimer's care. The study's completion in June 2018 positions Corium to leverage its findings for potential partnerships or licensing opportunities, particularly in the growing Alzheimer's therapeutics market, which is projected to expand significantly due to increasing prevalence rates. Competitive analysis indicates that while several oral formulations exist, the transdermal approach could differentiate Corium's offering, provided safety and efficacy are established.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03432195
Indication
Alzheimer's Disease
Modality
small molecule
Target
Acetylcholinesterase (AChE) inhibition via Donepezil, a piperidine derivative.
Intervention
Donepezil TDS
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.