TrialSignal
Clinical trial intelligence report
Biomarkers of Response to Taxotere in Hormone-Refractory Prostate Cancer
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 25, 2026
Report code
NCT01160705-Jun 25, 2026
NCT ID
NCT01160705
Status
COMPLETED
Phase
Completed
Sponsor
Cancer Trials Ireland
Executive brief
Investment-Ready Snapshot
The trial, sponsored by Cancer Trials Ireland, aimed to identify biomarkers predictive of response to docetaxel in patients with hormone-refractory prostate cancer. With an enrollment of 73 patients, the study's completion may provide valuable insights into the utility of mRNA as a predictive biomarker, potentially enhancing treatment personalization in this patient population. The findings could position docetaxel as a more targeted therapy, thereby improving patient outcomes and offering a competitive edge in the prostate cancer treatment market. Given the increasing focus on precision medicine, the results may attract interest from pharmaceutical companies looking to develop companion diagnostics or enhance existing therapies. The commercial implications extend to potential collaborations or licensing opportunities for biomarker development.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01160705
Indication
Metastatic Cancer
Modality
small molecule
Target
mRNA in circulating tumor cells as a biomarker for response to docetaxel in hormone-refractory prostate cancer
Intervention
docetaxel, RNA analysis, reverse transcriptase-polymerase chain reaction, circulating tumor cell analysis, laboratory biomarker analysis
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.