TrialSignal
Clinical trial intelligence report
Phase IIA Trial of Delayed Initiation of Olaparib Maintenance Therapy in Platinum Sensitive Recurrent Ovarian Cancer
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT04377087-Jun 24, 2026
NCT ID
NCT04377087
Status
TERMINATED
Phase
Phase 2A
Sponsor
Sarah E Taylor
Executive brief
Investment-Ready Snapshot
The trial aimed to evaluate the efficacy of delayed initiation of Olaparib maintenance therapy in patients with platinum-sensitive recurrent ovarian cancer. The market for PARP inhibitors, particularly in ovarian cancer, is significant, with increasing competition from other therapies. The slow enrollment leading to trial termination raises concerns about patient recruitment strategies and the potential for market saturation. Companies should assess the competitive landscape, particularly with other PARP inhibitors and emerging therapies targeting similar patient populations. Diligence should focus on understanding the implications of delayed treatment initiation on patient outcomes and healthcare costs.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04377087
Indication
Ovarian Cancer
Modality
small molecule
Target
Poly (ADP-ribose) polymerase (PARP) inhibitor, specifically targeting BRCA1/2 deficient tumor cells.
Intervention
Olaparib
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.