TrialSignal
Clinical trial intelligence report
A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Given Daily for 21 Days Followed by 7 Days Off Schedule in Patients With Advanced GI Tumors.
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT01927965-Jun 24, 2026
NCT ID
NCT01927965
Status
COMPLETED
Phase
Phase 1
Sponsor
Minneamrita Therapeutics LLC
Executive brief
Investment-Ready Snapshot
Minnelide™, developed by Minneamrita Therapeutics LLC, is currently undergoing a Phase 1 clinical trial aimed at establishing the maximum tolerated dose (MTD) and assessing dose-limiting toxicities (DLT) in patients with advanced gastrointestinal tumors. The market for advanced GI tumors is significant, with a growing demand for innovative therapies due to the limitations of current treatment options. If successful, Minnelide™ could position itself as a novel therapeutic agent in a competitive landscape that includes established chemotherapeutics and emerging biologics. The completion of this trial could pave the way for Phase 2 studies, enhancing investor interest and potential partnerships for further development and commercialization.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01927965
Indication
Advanced Gastrointestinal Tumors
Modality
small molecule
Target
Heat Shock Protein 70 (HSP70) and apoptosis pathways via caspase activation.
Intervention
Minnelide™ 001
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.