TrialSignal
Clinical trial intelligence report
Modulation of Beta-amyloid Levels in CSF and Plasma by GSK933776 in Patients With Mild Alzheimer's Disease or Mild Cognitive Impairment
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT01424436-Jun 24, 2026
NCT ID
NCT01424436
Status
COMPLETED
Phase
Phase 1
Sponsor
GlaxoSmithKline
Executive brief
Investment-Ready Snapshot
GSK933776, developed by GlaxoSmithKline, targets beta-amyloid modulation in patients with mild Alzheimer's disease and mild cognitive impairment. Given the increasing prevalence of Alzheimer's disease and the significant unmet medical need, this asset holds potential commercial value in a market projected to grow substantially. The competitive landscape includes other amyloid-targeting therapies, necessitating a thorough evaluation of GSK933776's efficacy and safety profile to establish a differentiated market position. The completion of this Phase 1 trial suggests a commitment to advancing the drug through clinical development, which may attract partnerships or investment opportunities.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT01424436
Indication
Alzheimer's Disease
Modality
protein therapy
Target
Beta-amyloid levels modulation in cerebrospinal fluid (CSF) and plasma.
Intervention
GSK933776, GSK933776, GSK933776
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.