TrialSignal
Clinical trial intelligence report
Investigation of Inflammation Using [C-11]-CS1P1
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT04517552-Jun 24, 2026
NCT ID
NCT04517552
Status
ACTIVE_NOT_RECRUITING
Phase
Phase 1
Sponsor
Tammie L. S. Benzinger, MD, PhD
Executive brief
Investment-Ready Snapshot
The clinical trial investigates the noninvasive imaging of S1P1 using the radiotracer [C-11]-CS1P1, which is critical for understanding its role in neuroinflammation and neurodegeneration, particularly in multiple sclerosis (MS). The relevance of S1P1 has been underscored by the FDA approval of fingolimod (FTY720) for RR-MS, indicating a growing market for S1P1-targeted therapies and diagnostics. The successful development of [C-11]-CS1P1 could position the sponsor favorably within the neuroimaging market, potentially leading to partnerships with pharmaceutical companies focused on MS and other neurodegenerative diseases. Competitive implications include the need to monitor other imaging agents targeting similar pathways and the potential for collaboration with entities developing S1P1 modulators.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04517552
Indication
Alzheimer Disease
Modality
small molecule
Target
Sphingosine-1-phosphate receptor 1 (S1P1)
Intervention
[11C]-CS1P1
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.