TrialSignal
Clinical trial intelligence report
A Phase I, Open-label Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LUCAR-G39P, a Dual-targeted Cell Preparation Targeting CD19/CD20, in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT06295549-Jun 24, 2026
NCT ID
NCT06295549
Status
TERMINATED
Phase
Phase 1
Sponsor
The First Affiliated Hospital with Nanjing Medical University
Executive brief
Investment-Ready Snapshot
LUCAR-G39P is positioned in the competitive landscape of CAR-T therapies, specifically targeting relapsed/refractory B-cell non-Hodgkin lymphoma (NHL). Given the increasing prevalence of NHL and the limitations of existing therapies, this dual-targeted approach may enhance efficacy and reduce relapse rates. The trial's termination after achieving proof of concept suggests potential for further development, possibly leading to a Phase II study. Collaboration with Nanjing Legend Biotech Co. indicates strategic partnerships that may enhance market access and resource allocation. The asset's success could capture a significant share of the CAR-T market, which is projected to grow substantially in the coming years.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06295549
Indication
Relapsed and Refractory B-cell Non-Hodgkin Lymphoma
Modality
protein therapy
Target
CD19/CD20 dual-targeted cell preparation
Intervention
LUCAR-G39P cells product
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.