TrialSignal
Clinical trial intelligence report
Lorcaserin in Obesity: Identification of CNS Targets Using fMRI
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT02400359-Jun 24, 2026
NCT ID
NCT02400359
Status
ACTIVE_NOT_RECRUITING
Phase
Phase 4
Sponsor
Beth Israel Deaconess Medical Center
Executive brief
Investment-Ready Snapshot
Lorcaserin (marketed as Belviq) is positioned in the obesity management market, which is experiencing significant growth due to rising obesity rates globally. The drug's unique mechanism, targeting CNS receptors without cardiovascular side effects, differentiates it from previous weight-loss medications. However, its market presence may be challenged by newer entrants, particularly GLP-1 receptor agonists, which have shown superior efficacy in weight loss and metabolic control. The ongoing clinical trial aims to elucidate lorcaserin's CNS effects, potentially enhancing its value proposition and informing future marketing strategies. Investors should monitor the trial's outcomes closely, as positive results could revitalize interest and sales in a competitive landscape.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT02400359
Indication
Obesity
Modality
small molecule
Target
Serotonin 2C receptors (5-HT2C), primarily in the central nervous system, involved in appetite regulation.
Intervention
Lorcaserin HCl, Placebo
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.