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Clinical trial intelligence report
An Open-Label, Nonrandomized Study To Evaluate The Potential Pharmacokinetic Interaction Between SAM-531 and Gemfibrozil, A Cytochrome P-450 2C8 Inhibitor, When Coadministered Orally To Healthy Young Adult Subjects
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT00966966-Jun 24, 2026
NCT ID
NCT00966966
Status
COMPLETED
Phase
Phase 1
Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Executive brief
Investment-Ready Snapshot
The study evaluates the pharmacokinetic interaction between SAM-531, a compound under investigation for potential therapeutic applications, and Gemfibrozil, a known cytochrome P-450 2C8 inhibitor. Given the increasing focus on drug-drug interactions in drug development, this study may provide critical insights into the safety and efficacy profiles of SAM-531, particularly in populations that may be on concurrent medications. The results could influence market positioning and regulatory strategies for SAM-531, especially in the context of diseases like Alzheimer’s, where polypharmacy is common. The completion of this trial may enhance Pfizer's portfolio in neurology and related therapeutic areas, potentially leading to strategic partnerships or licensing opportunities.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT00966966
Indication
Healthy
Modality
small molecule
Target
Cytochrome P-450 2C8
Intervention
SAM-531 and gemfibrozil
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.