TrialSignal
Clinical trial intelligence report
A Phase 1, Single-center, Open-label, 2-part, 2-treatment Period, 1-sequence, Cross-over, Drug-drug Interaction Study to Investigate the Effect of Erythromycin on SAR443820 (Part A) and the Effect of Itraconazole on SAR443820 (Part B) in Healthy Adult Participants
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT05797753-Jun 24, 2026
NCT ID
NCT05797753
Status
COMPLETED
Phase
Phase 1
Sponsor
Sanofi
Executive brief
Investment-Ready Snapshot
SAR443820 is currently undergoing a Phase 1 clinical trial to assess its pharmacokinetic profile when co-administered with CYP3A4 inhibitors, specifically erythromycin and itraconazole. This study is crucial for understanding potential drug-drug interactions that could affect the therapeutic efficacy and safety profile of SAR443820. Given the competitive landscape in the treatment of conditions such as Amyotrophic Lateral Sclerosis (ALS), successful outcomes could position Sanofi favorably in the market. The trial's completion and subsequent data could enhance investor confidence and inform strategic partnerships or licensing opportunities, particularly if SAR443820 demonstrates a favorable safety and efficacy profile.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT05797753
Indication
Amyotrophic Lateral Sclerosis
Modality
small molecule
Target
Cytochrome P450 3A4 (CYP3A4) enzyme inhibition
Intervention
SAR443820, SAR443820, Erythromycin ethyl succinate, Itraconazole
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.