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A Clinical Study to Evaluate the Safety and Tolerability of SCT-001 CAR-T Cells in Patients with Recurrent and Refractory Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Peritoneal Cancer.
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT06846424-Jun 24, 2026
NCT ID
NCT06846424
Status
NOT_YET_RECRUITING
Phase
Phase 1
Sponsor
Shanghai Gynecologic Oncology Group
Executive brief
Investment-Ready Snapshot
SCT-001 CAR-T cell therapy is positioned to address a significant unmet need in the treatment of recurrent and refractory epithelial ovarian, fallopian tube, and peritoneal cancers, which are often resistant to standard therapies. The open-label, dose-escalation design allows for the evaluation of safety and preliminary efficacy, which could provide a competitive edge in the CAR-T landscape, particularly in solid tumors. The dual administration routes (intraperitoneal and intravenous) may enhance patient accessibility and treatment personalization. The market for ovarian cancer therapies is growing, with increasing investment in immunotherapies, suggesting potential for substantial commercial success if efficacy is demonstrated. However, the competitive landscape includes established players in CAR-T and emerging therapies targeting similar indications, necessitating a robust clinical outcome to differentiate SCT-001.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06846424
Indication
Ovarian Cancer
Modality
cell therapy
Target
TAG-72 (tumor-associated glycoprotein 72), a target for CAR-T cell therapy in epithelial ovarian, fallopian tube, and peritoneal cancers.
Intervention
SCT-001 CAR-T cells
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.