TrialSignal
Clinical trial intelligence report
An Open Clinical Study on the Safety and Efficacy of Autologous GD2-CAR T Cells in the Treatment of Relapsed Refractory Neuroblastoma
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT06684639-Jun 24, 2026
NCT ID
NCT06684639
Status
RECRUITING
Phase
Early Phase 1
Sponsor
The General Hospital of Western Theater Command
Executive brief
Investment-Ready Snapshot
The clinical trial, sponsored by The General Hospital of Western Theater Command in collaboration with Yake Biotechnology Ltd., aims to address the significant unmet medical need for patients with relapsed refractory neuroblastoma. With GD2 being a highly specific target for neuroblastoma immunotherapy, the successful development of GD2-CAR T cells could position the sponsors favorably in the competitive landscape of CAR T-cell therapies. The trial is currently recruiting, with an estimated enrollment of 30 patients, indicating a focused approach to early-stage development. The market for neuroblastoma therapies is underserved, particularly for high-risk patients, suggesting potential for substantial commercial opportunity if efficacy and safety are demonstrated.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06684639
Indication
Neuroblastoma
Modality
cell therapy
Target
GD2 (dissialic ganglioside) expressed by neuroectodermal tumors, specifically targeting neuroblastoma cells.
Intervention
GD2-CAR-T cell
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.