TrialSignal
Clinical trial intelligence report
DOS [Dosing Optimization Study]: Open-label, Single-arm, Proof-of-Concept Dosing Study of Afrezza® in Adult Subjects 18 Years and Older With Type 1 or Type 2 Diabetes Mellitus
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 24, 2026
Report code
NCT04849845-Jun 24, 2026
NCT ID
NCT04849845
Status
COMPLETED
Phase
Phase 4
Sponsor
Mannkind Corporation
Executive brief
Investment-Ready Snapshot
Mannkind Corporation's Afrezza is positioned in the competitive landscape of diabetes management, particularly for patients with Type 1 and Type 2 diabetes. The Dosing Optimization Study (MKC-TI-191) aims to enhance the understanding of Afrezza's efficacy in conjunction with basal insulin, potentially improving patient adherence and glycemic control. The results could strengthen Afrezza's market positioning against traditional insulin therapies and other inhaled insulin products. The study's completion and subsequent data may attract interest from healthcare providers and payers, influencing market uptake and reimbursement strategies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT04849845
Indication
Diabetes Mellitus, Type 1
Modality
combination therapy
Target
Inhaled insulin delivery via Technosphere technology.
Intervention
Afrezza Dose 1, Afrezza Dose 2
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.