TrialSignal
Clinical trial intelligence report
Phase 4, Open Label, Non-comparative, Interventional, Multicenter Study to Evaluate the Safety of Dostarlimab in Adult Patients in India With Mismatch Repair Deficient (dMMR)/Microsatellite Instability-high (MSI-H) Recurrent or Advanced Endometrial Cancer (EC) That Has Progressed on or Following Prior Treatment With a Platinum-containing Regimen
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 20, 2026
NCT ID
NCT06897527
Status
NOT_YET_RECRUITING
Phase
Phase 4
Sponsor
GlaxoSmithKline
Executive brief
Investment-Ready Snapshot
Dostarlimab, an anti-PD-1 monoclonal antibody, is being evaluated for safety in adult patients with dMMR/MSI-H recurrent or advanced endometrial cancer in India. This study is significant as it targets a niche patient population that has limited treatment options following platinum-based therapies. The market for endometrial cancer therapeutics is growing, particularly in regions like India where the incidence is rising. GSK's positioning with dostarlimab could enhance its portfolio in immuno-oncology, especially given the increasing demand for personalized medicine. However, the competitive landscape includes other PD-1/PD-L1 inhibitors, necessitating a strong safety profile and differentiation in efficacy to capture market share.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06897527
Indication
Neoplasms, Endometrial
Modality
small molecule
Target
Programmed Death-1 (PD-1) receptor
Intervention
Dostarlimab
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.