TrialSignal
Clinical trial intelligence report
Phase 4, Open Label, Non-comparative, Interventional, Multicenter Study to Evaluate the Safety of Dostarlimab in Adult Patients in India With Mismatch Repair Deficient (dMMR)/Microsatellite Instability-high (MSI-H) Recurrent or Advanced Endometrial Cancer (EC) That Has Progressed on or Following Prior Treatment With a Platinum-containing Regimen
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Aug 04, 2026
Report code
NCT06897527-Aug 04, 2026
NCT ID
NCT06897527
Status
NOT_YET_RECRUITING
Phase
Phase 4
Sponsor
GlaxoSmithKline
Executive brief
Investment-Ready Snapshot
Dostarlimab, a PD-1 inhibitor, is being evaluated in a Phase 4 trial for its safety in adult patients with dMMR/MSI-H recurrent or advanced endometrial cancer in India. This study is significant as it targets a specific patient population that has limited treatment options following platinum-based therapies. The Indian market for oncology therapeutics is growing, and successful outcomes could enhance GSK's positioning in the immuno-oncology space, particularly in emerging markets. The trial's non-comparative design may limit direct competitive insights but could provide valuable safety data that supports broader use of dostarlimab in this indication. The estimated enrollment of 100 patients indicates a focused approach, potentially allowing for quicker data collection and analysis.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06897527
Indication
Neoplasms, Endometrial
Modality
small molecule
Target
Programmed cell death protein 1 (PD-1)
Intervention
Dostarlimab
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.