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A Clinical Study on CRISPR/Cas9 Instantaneous Gene Editing Therapy to Primary Open-angle Glaucoma With Elevated Intraocular Pressure and MYOC Gene Mutation
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 20, 2026
NCT ID
NCT06465537
Status
RECRUITING
Phase
Phase 1/2
Sponsor
Shanghai BDgene Co., Ltd.
Executive brief
Investment-Ready Snapshot
Shanghai BDgene Co., Ltd. is advancing its CRISPR/Cas9 gene editing therapy, BD113vLVP, targeting primary open-angle glaucoma (POAG) with MYOC gene mutations. The therapy addresses a significant unmet medical need in glaucoma management, particularly for patients with elevated intraocular pressure (IOP) resistant to conventional treatments. The global glaucoma therapeutics market is projected to grow, driven by increasing prevalence and advancements in gene therapy. BDgene's innovative approach positions it competitively within the gene therapy landscape, although it faces potential competition from established pharmaceutical companies and emerging biotech firms focusing on ocular diseases. Diligence is warranted regarding regulatory pathways and potential market access challenges, particularly in light of the evolving landscape of gene therapies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06465537
Indication
Primary Open Angle Glaucoma
Modality
gene therapy
Target
MYOC gene mutation in primary open-angle glaucoma (POAG) patients, utilizing CRISPR/Cas9 technology for gene editing.
Intervention
BD113vVLP
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.