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Clinical trial intelligence report
A Clinical Study on CRISPR/Cas9 Instantaneous Gene Editing Therapy to Primary Open-angle Glaucoma With Elevated Intraocular Pressure and MYOC Gene Mutation
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Aug 04, 2026
Report code
NCT06465537-Aug 04, 2026
NCT ID
NCT06465537
Status
UNKNOWN
Phase
Phase 1/2
Sponsor
Shanghai BDgene Co., Ltd.
Executive brief
Investment-Ready Snapshot
The clinical trial sponsored by Shanghai BDgene Co., Ltd. aims to evaluate the safety and preliminary efficacy of BD113vLVP, a CRISPR/Cas9-based gene editing therapy, in patients with primary open-angle glaucoma (POAG) associated with MYOC gene mutations. The market for glaucoma treatments is significant, with a growing demand for innovative therapies that address the underlying genetic causes of the disease. If successful, BD113vLVP could position itself as a first-in-class therapy, potentially capturing a substantial share of the glaucoma treatment market, especially among patients with MYOC mutations. Competitive analysis indicates a limited number of gene-editing therapies targeting ocular conditions, suggesting a favorable landscape for BDgene's asset. However, the trial's outcomes will be critical for investor confidence and future funding opportunities.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT06465537
Indication
Primary Open Angle Glaucoma
Modality
gene therapy
Target
MYOC gene mutation; CRISPR/Cas9 gene editing technology (BD113vLVP) targeting intraocular pressure regulation in primary open-angle glaucoma.
Intervention
BD113vVLP
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.