TrialSignal
Clinical trial intelligence report
Clinical Trial of Intraperitoneal CAR-T Cells Infusion for the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Aug 04, 2026
Report code
NCT03563326-Aug 04, 2026
NCT ID
NCT03563326
Status
UNKNOWN
Phase
Phase 1
Sponsor
Jian-Kun Hu
Executive brief
Investment-Ready Snapshot
The clinical trial aims to evaluate the safety and efficacy of EpCAM CAR-T cell therapy in patients with advanced gastric cancer exhibiting peritoneal metastasis. Given the high mortality rates associated with gastric cancer, particularly in China, successful outcomes could position this therapy as a novel treatment option in a market with significant unmet needs. The trial's focus on a specific patient population that has failed standard therapies may enhance its appeal to oncologists and patients alike. Competitive analysis indicates that while CAR-T therapies are gaining traction in hematological malignancies, their application in solid tumors remains limited, providing a potential first-mover advantage for this asset if successful. Diligence should focus on regulatory pathways and reimbursement strategies for CAR-T therapies in solid tumors.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03563326
Indication
Neoplasm, Stomach
Modality
cell therapy
Target
Epithelial Cell Adhesion Molecule (EpCAM)
Intervention
CAR-T cells targeting EpCAM, Chemotherapy
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.