TrialSignal
Clinical trial intelligence report
Clinical Trial of Intraperitoneal CAR-T Cells Infusion for the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 20, 2026
NCT ID
NCT03563326
Status
UNKNOWN
Phase
Phase 1
Sponsor
Jian-Kun Hu
Executive brief
Investment-Ready Snapshot
The clinical trial, sponsored by Jian-Kun Hu at West China Hospital, aims to evaluate the safety and efficacy of EpCAM-targeted CAR-T cell therapy for advanced gastric cancer with peritoneal metastasis. Given the high incidence of gastric cancer in China and the poor prognosis associated with peritoneal metastasis, this trial addresses a significant unmet medical need. If successful, the therapy could capture a substantial share of the gastric cancer treatment market, particularly in regions with high prevalence. The competitive landscape includes other CAR-T therapies and emerging immunotherapies, necessitating robust clinical data to establish differentiation. Diligence should focus on regulatory pathways, potential partnerships for commercialization, and the scalability of CAR-T cell manufacturing.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT03563326
Indication
Neoplasm, Stomach
Modality
cell therapy
Target
Epithelial Cell Adhesion Molecule (EpCAM)
Intervention
CAR-T cells targeting EpCAM, Chemotherapy
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.