This observational study, sponsored by Shandong University of Traditional Chinese Medicine, aims to elucidate the role of SIRT3 in differentiating subtypes of poor ovarian response (POR) during IVF. The findings could enhance understanding of ovarian response mechanisms and potentially lead to improved IVF outcomes, thereby addressing a significant market need in reproductive health. The study's focus on metabolic profiling may also open avenues for novel therapeutic strategies targeting metabolic pathways in infertility. Given the increasing demand for personalized medicine in reproductive technologies, the insights gained could position the sponsor favorably within the competitive landscape of fertility treatments.