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Clinical trial intelligence report
Placebo-Controlled, Double-Blind Study of Galantamine (R113675) in the Treatment of Alzheimer's Disease.
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Aug 04, 2026
Report code
NCT00301574-Aug 04, 2026
NCT ID
NCT00301574
Status
COMPLETED
Phase
Phase 3
Sponsor
Janssen Pharmaceutical K.K.
Executive brief
Investment-Ready Snapshot
Galantamine, developed by Janssen Pharmaceutical K.K., is positioned in the competitive landscape of Alzheimer's disease treatments, which includes established therapies such as donepezil and rivastigmine. The Phase 3 study aims to demonstrate the efficacy and safety of two fixed doses (16mg/day and 24mg/day) compared to placebo, potentially expanding its market share in a growing sector driven by increasing Alzheimer's prevalence. The successful completion of this trial may enhance Janssen's portfolio and provide a competitive edge, particularly if the results indicate significant improvements in cognitive function. Given the aging global population, the market for Alzheimer's treatments is expected to expand, making this asset a strategic focus for Janssen.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT00301574
Indication
Alzheimer Disease
Modality
small molecule
Target
Galantamine targets acetylcholinesterase, an enzyme that breaks down acetylcholine, thereby increasing acetylcholine levels in the brain, which is beneficial for cognitive function in Alzheimer's disease.
Intervention
galantamine
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.