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A Phase Ib Study to Explore the Safety, Tolerability, and Pharmacokinetics of HS-20093 Combination With HRS-5041 in Patients With Advanced Prostate Cancer
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Aug 04, 2026
Report code
NCT07115446-Aug 04, 2026
NCT ID
NCT07115446
Status
RECRUITING
Phase
Phase 1b
Sponsor
Hansoh BioMedical R&D Company
Executive brief
Investment-Ready Snapshot
Hansoh BioMedical R&D Company is advancing HS-20093, a fully humanized IgG1 antibody-drug conjugate (ADC) targeting B7-H3, in combination with HRS-5041, a PROTAC targeting androgen receptors, for the treatment of advanced prostate cancer. This dual-target approach may provide a competitive edge in a market characterized by a high unmet need for effective therapies in metastatic castration-resistant prostate cancer (mCRPC). The study's focus on safety, tolerability, and pharmacokinetics will be critical in establishing the therapeutic profile and potential market positioning. Given the increasing incidence of prostate cancer and the limitations of current therapies, successful outcomes could lead to significant commercial opportunities, particularly in regions with high disease prevalence.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07115446
Indication
Advanced Prostate Cancer
Modality
small molecule
Target
B7-H3 (CD276) and androgen receptors (AR)
Intervention
HS-20093, HRS-5041
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.