TrialSignal
Clinical trial intelligence report
An Open-Label, Multicenter Phase Ib/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of QLH12016 in Combination With Novel Hormonal Agent in Subjects With Advanced Prostate Cancer
Source-linked diligence brief with registry provenance, taxonomy normalization and premium analytical context.
Generated
Jun 20, 2026
NCT ID
NCT07104110
Status
NOT_YET_RECRUITING
Phase
Phase 1/2
Sponsor
Qilu Pharmaceutical Co., Ltd.
Executive brief
Investment-Ready Snapshot
QLH12016, an investigational oral AR PROTAC, is being evaluated in combination with established hormonal agents (abiraterone acetate and enzalutamide) for advanced prostate cancer. The trial's focus on safety, tolerability, and preliminary antitumor activity positions it within a competitive landscape dominated by existing therapies. The prostate cancer market is substantial, with ongoing demand for novel treatments that can overcome resistance mechanisms associated with current therapies. Successful outcomes could enhance Qilu Pharmaceutical's portfolio and provide a strategic advantage in a market characterized by high unmet needs and significant competition from other emerging therapies.
Source & freshness
Provenance
https://clinicaltrials.gov/study/NCT07104110
Indication
Prostatic Neoplasms
Modality
small molecule
Target
Androgen Receptor (AR) modulation via PROTAC technology
Intervention
QLH12016, abiraterone acetate, enzalutamide
Source record
Protocol Description
Detailed source ingestion pending.
Source record
Outcome Measures
Detailed source ingestion pending.
Source record
Eligibility
Detailed source ingestion pending.
AI analysis
Known Results And Readout Context
Detailed source ingestion pending.
IP intelligence
Patent And IP Landscape
Detailed source ingestion pending.
Source record
Contacts
Detailed source ingestion pending.